Monday, February 11, 2008

Results of radiotherapy for drooling in ALS

Stalpers LJA, Moser EC. Neurology 2002; 58: 1308.

19 patients with ALS and sialorrhea were treated, all had failed anticholinergic drugs. They got 12 Gy in 2 fractions once a week. That is equivalent to 16 Gy in 8 fractions. 74 % had a complete or partial response. AE's included parotid area pain and mouth dryness. (Netherlands).

Blogger comment question: Can one dare use botox in ALS patients?

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