Bacterial and fungal meningitis in patients with cancer

Safdieh JE, Mead PA, Sepkowitz KA et al. Neurology 2008; 943-947. High points-- only five percent of cases had the triad of fever, nuchal rigidity and mental status changes. VP shunt patients usually presented with mental status changes. Most patients had had prior neurosurgery. organisms included more gram positive infections and a smattering of diverse other organisms. CSF response was often muted.