Saturday, April 23, 2011

myoclonus fromgabapentin

Myoclonus Associated with the Use of Gabapentin

v Of 104 consecutive patients treated with
gabapentin, 13 (12.5%) developed myoclonus
v All patients (age 14 to 41 years) had refractory
partial epilepsy, 6 had a static encephalopathy
v Myoclonus was multifocal in 10, contralateral to
the epilepticus focus in 3
v Myoclonus persisted for as long as gabapentin
was continued. Disappeared on drug withdrawal.
v An EEG recording in 3 patients showed no
J. Asconapé et al., Epilepsia 2000:41:479-82

No comments: